A study of the role of DIO1 and DIO2 polymorphism in thyroid cancer and drug response to therapy in the Saudi population

Background: Deiodinases comprise a group of selenoproteins that regulate the bioavailability of active thyroid hormones (TH) in a time and tissue specific fashion. They increase the hormonal activity by metabolizing their inactive precursors to active forms or terminate their activity by deactivatin...

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Bibliographic Details
Main Authors: Maha M. AlRasheed, Ashwaq AlAnzi, Rawan AlShalhoub, Norah Abanmy, Dana Bakheet
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016419300763