Magnetic Resonance Imaging Identifies Differential Response to Pro-Oxidant Chemotherapy in a Xenograft Model

Induction of oxidative stress is a key component of cancer therapy. Pro-oxidant drugs have been demonstrated to enhance the efficacy of radiotherapy and chemotherapy. An emerging concept is that therapeutic outcomes are dictated by the differential redox buffering reserve in subpopulations of malign...

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Bibliographic Details
Main Authors: Terry H. Landowski, Gerald P. Guntle, Dezheng Zhao, Bhumasamudram Jagadish, Eugene A. Mash, Robert T. Dorr, Natarajan Raghunand
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652331630016X