Nanoscale Investigation of DNA Demethylation in Leukemia Cells by Means of Ultrasensitive Vibrational Spectroscopy

Nanoscale Investigation of DNA Demethylation in Leukemia Cells by Means of Ultrasensitive Vibrational Spectroscopy

DNA methylation is a crucial epigenetic hallmark of cancer development but the experimental methods able to prove nanoscale modifications are very scarce. Over time, Raman and its counterpart, surface-enhanced Raman scattering (SERS), became one of the most promising techniques capable to investigat...

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Bibliographic Details
Main Authors: Anca Onaciu, Valentin Toma, Cristian Moldovan, Adrian Bogdan Țigu, Diana Cenariu, Carina Culic, Rareș Mario Borșa, Luca David, Gabriela Fabiola Știufiuc, Romulus Tetean, Ciprian Tomuleasa, Rareș Ionuț Știufiuc
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Sensors
Subjects:
leukemia
5-azacytidine
Raman spectroscopy
SERS
DNA demethylation
Online Access:https://www.mdpi.com/1424-8220/23/1/346

Internet

https://www.mdpi.com/1424-8220/23/1/346

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