A novel cardiovascular systems model to quantify drugs effects on the inter‐relationship between contractility and other hemodynamic variables

A novel cardiovascular systems model to quantify drugs effects on the inter‐relationship between contractility and other hemodynamic variables

Abstract The use of systems‐based pharmacological modeling approaches to characterize mode‐of‐action and concentration‐effect relationships for drugs on specific hemodynamic variables has been demonstrated. Here, we (i) expand a previously developed hemodynamic system model through integration of ca...

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Bibliographic Details
Main Authors: Yu Fu, Hadi Taghvafard, Medhat M. Said, Eric I. Rossman, Teresa A. Collins, Stéphanie Billiald‐Desquand, Derek Leishman, Piet H. van derGraaf, J. G. Coen vanHasselt, Nelleke Snelder
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12774

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https://doi.org/10.1002/psp4.12774

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