Immunosuppression Has Long-Lasting Effects on Circulating Follicular Regulatory T Cells in Kidney Transplant Recipients

Immunosuppression Has Long-Lasting Effects on Circulating Follicular Regulatory T Cells in Kidney Transplant Recipients

Background: FoxP3+ follicular regulatory T cells (Tfr) have been identified as the cell population controlling T follicular helper (Tfh) cells and B cells which, are both involved in effector immune responses against transplanted tissue.Methods: To understand the biology of Tfr cells in kidney trans...

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Bibliographic Details
Main Authors: Qian Niu, Aleixandra Mendoza Rojas, Marjolein Dieterich, Dave L. Roelen, Marian C. Clahsen-van Groningen, Lanlan Wang, Teun van Gelder, Dennis A. Hesselink, Nicole M. van Besouw, Carla C. Baan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
antibody mediated rejection
anti-rejection therapy
donor specific antibodies
flow cytometry
circulating Tfr
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01972/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01972/full

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