Activation of caspase-1 dependent interleukins in developmental brain trauma

Activation of caspase-1 dependent interleukins in developmental brain trauma

Focal mechanical cortical trauma triggers diffuse apoptotic neurodegeneration in the developing rat brain which is associated with invasion of brain tissue with inflammatory mediators. We hypothesized that caspase-1 and the two caspase-1-processed cytokines, interleukin (IL)-1β and IL-18, are involv...

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Bibliographic Details
Main Authors: Marco Sifringer, Vanya Stefovska, Stefanie Endesfelder, Philip F. Stahel, Kerstin Genz, Mark Dzietko, Chrysanthy Ikonomidou, Ursula Felderhoff-Mueser
Format: Article
Language:English
Published: Elsevier 2007-03-01
Series:Neurobiology of Disease
Subjects:
Apoptosis
Infant brain trauma
Interleukin-1β
Interleukin-18
Caspase-1
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610600297X

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http://www.sciencedirect.com/science/article/pii/S096999610600297X

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