Human Hepatocyte Nuclear Factors (HNF1 and LXRb) Regulate CYP7A1 in HIV-Infected Black South African Women with Gallstone Disease: A Preliminary Study

Female sex, high estrogen levels, aging, obesity, and dyslipidemia are some of the risk factors associated with gallstone formation. HIV-infected patients on combination antiretroviral therapy (cART) are more prone to hypercholesterolemia. Bile acid synthesis is initiated by cholesterol 7-alpha hydr...

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Bibliographic Details
Main Authors: Suman Mewa Kinoo, Pragalathan Naidoo, Bhugwan Singh, Anil Chuturgoon, Savania Nagiah
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/2/273