Prostacyclin analogues decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation

Prostacyclin analogues decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation

Prostacyclin (PGI2) analogues (epoprostenol, treprostonil, iloprost) are the cornerstone of pulmonary arterial hypertension (PAH) treatment. PGI2 analogues inhibit platelet reactivity, but their impact on coagulation and fibrinolysis parameters has not been elucidated. We compared platelet reactivit...

Full description

Bibliographic Details
Main Authors: Aleksander Siniarski, Aleksandra Gąsecka, Miłosz Starczyński, Marta Banaszkiewicz, Szymon Darocha, Adam Torbicki, Marcin Kurzyna, Krzysztof J. Filipiak, Jadwiga Nessler, Grzegorz Gajos
Format: Article
Language:English
Published: Taylor & Francis Group 2022-10-01
Series:Platelets
Subjects:
fibrin clot
fibrinolysis
platelet reactivity
prostacyclin analogues
pulmonary arterial hypertension
thrombin generation
Online Access:http://dx.doi.org/10.1080/09537104.2022.2042234

Internet

http://dx.doi.org/10.1080/09537104.2022.2042234

Similar Items