Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases

Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases

Hydroxylation of prolines to 4-trans-hydroxyproline (Hyp) is mediated by prolyl-4 hydroxylases (P4Hs). In plants, Hyps occur in Hydroxyproline-rich glycoproteins (HRGPs), and are frequently O-glycosylated. While both modifications are important, e.g. for cell wall stability, they are undesired in pl...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Christine Rempfer, Sebastian N.W. Hoernstein, Nico van Gessel, Andreas W. Graf, Roxane P. Spiegelhalder, Anne Bertolini, Lennard L. Bohlender, Juliana Parsons, Eva L. Decker, Ralf Reski
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Elsevier 2024-12-01
Saila:Computational and Structural Biotechnology Journal
Gaiak:
Biopharmaceutical
Erythropoietin
O-glycosylation
Plant-made pharmaceutical
Posttranslational protein modification
Prolyl-hydroxylation
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2001037024002113

Internet

http://www.sciencedirect.com/science/article/pii/S2001037024002113

Antzeko izenburuak