The Effect of Different Glucose Concentrations on the Antiproliferative Activity of Metformin in MCF-7 Breast Cancer Cells

The Effect of Different Glucose Concentrations on the Antiproliferative Activity of Metformin in MCF-7 Breast Cancer Cells

The glucose-lowering drug metformin has been reported to have anticancer properties through unknown mechanisms. Other unknown factors that may influence its anticancer potential include the glycemic status of the patient. Therefore, the objective of this study is to determine the effect of different...

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Bibliographic Details
Main Authors: Sholpan Nurzhan, Zhibek Bekezhankyzy, Hong Ding, Nurken Berdigaliyev, Shynggys Sergazy, Alexander Gulyayev, Zarina Shulgau, Christopher R. Triggle, Mohamad Aljofan
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
metformin
apoptosis
antiproliferative
mTOR
BCL-2
glucose
Online Access:https://www.mdpi.com/1999-4923/15/9/2186

Internet

https://www.mdpi.com/1999-4923/15/9/2186

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