The Mysterious Ways of ErbB2/HER2 Trafficking
The EGFR- or ErbB-family of receptor tyrosine kinases consists of EGFR/ErbB1, ErbB2/HER2, ErbB3/HER3 and ErbB4/HER4. Receptor activation and downstream signaling are generally initiated upon ligand-induced receptor homo- or heterodimerization at the plasma membrane, and endocytosis and intracellular...
Päätekijät: | , |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
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MDPI AG
2014-08-01
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Sarja: | Membranes |
Aiheet: | |
Linkit: | http://www.mdpi.com/2077-0375/4/3/424 |