Effect of chronic intermittent hypoxia-induced HIF-1α/ATAD2 expression on lung cancer stemness

Abstract Background Obstructive sleep apnea is associated with increased lung cancer incidence and mortality. Cancer stem cells (CSCs) are characterized by their self-renewing ability, which contributes to metastasis, recurrence, and drug resistance. ATPase family AAA domain-containing protein 2 (AT...

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Bibliographic Details
Main Authors: Shengyu Hao, Fan Li, Pan Jiang, Jian Gao
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-022-00345-5