Major molecular response achievement in CML Patients can be predicted by BCR-ABL1/ABL1 or BCR-ABL1/GUS ratio at an earlier time point of follow-up than currently recommended.

Major molecular response achievement in CML Patients can be predicted by BCR-ABL1/ABL1 or BCR-ABL1/GUS ratio at an earlier time point of follow-up than currently recommended.

Recent studies demonstrate that early molecular response to tyrosine-kinase inhibitors is strongly predictive of outcome in chronic myeloid leukemia patients and that early response landmarks may identify patients at higher risk for transformation who would benefit from an early switch to second-lin...

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Bibliographic Details
Main Authors: Sarah Huet, Pascale Cony-Makhoul, Maël Heiblig, Isabelle Tigaud, Sophie Gazzo, Amine Belhabri, Denis Souche, Mauricette Michallet, Jean-Pierre Magaud, Sandrine Hayette, Franck Nicolini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0106250

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https://doi.org/10.1371/journal.pone.0106250

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