Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza

Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza

Abstract Influenza and SARS-CoV-2 are two major respiratory pathogens that cocirculate in humans and cause serious illness with the potential to exacerbate disease in the event of co-infection. To develop a bivalent vaccine, capable of protecting against both infections, we inserted the receptor-bin...

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Bibliographic Details
Main Authors: Ekaterina Stepanova, Irina Isakova-Sivak, Daria Mezhenskaya, Sergei Niskanen, Victoria Matyushenko, Ekaterina Bazhenova, Alexandra Rak, Pei Fong Wong, Polina Prokopenko, Tatiana Kotomina, Elena Krutikova, Sergei Legotskiy, Bogdan Neterebskii, Tatiana Ostroukhova, Konstantin Sivak, Yana Orshanskaya, Kirill Yakovlev, Larisa Rudenko
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Virology Journal
Subjects:
SARS-CoV-2
COVID-19
Influenza
Bivalent vaccine
Recombinant influenza virus
Virus vectored vaccine
Online Access:https://doi.org/10.1186/s12985-024-02350-w

Internet

https://doi.org/10.1186/s12985-024-02350-w

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