Developmental diet regulates Drosophila lifespan via lipid autotoxins

The diet consumed during development can have long-lasting effects on adult physiology. Here, the authors show that developmental undernutrition in Drosophila extends lifespan by inhibiting the production of toxic lipids, called autotoxins, on the adult body surface.

Bibliographic Details
Main Authors: M. Irina Stefana, Paul C. Driscoll, Fumiaki Obata, Ana Raquel Pengelly, Clare L. Newell, James I. MacRae, Alex P. Gould
Format: Article
Language:English
Published: Nature Portfolio 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01740-9