Developmental diet regulates Drosophila lifespan via lipid autotoxins
The diet consumed during development can have long-lasting effects on adult physiology. Here, the authors show that developmental undernutrition in Drosophila extends lifespan by inhibiting the production of toxic lipids, called autotoxins, on the adult body surface.
Main Authors: | M. Irina Stefana, Paul C. Driscoll, Fumiaki Obata, Ana Raquel Pengelly, Clare L. Newell, James I. MacRae, Alex P. Gould |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01740-9 |
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