Emerging Concepts in Immune Thrombocytopenia

Emerging Concepts in Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune disease defined by low platelet counts which presents with an increased bleeding risk. Several genetic risk factors (e.g., polymorphisms in immunity-related genes) predispose to ITP. Autoantibodies and cytotoxic CD8+ T cells (Tc) mediate the anti-platel...

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Bibliographic Details
Main Authors: Maurice Swinkels, Maaike Rijkers, Jan Voorberg, Gestur Vidarsson, Frank W. G. Leebeek, A. J. Gerard Jansen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
immune thrombocytopenia
immune thrombocytopenic purpura
autoantibodies
CD8+ T cells
autoimmunity
ITP
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00880/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00880/full

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