BCATc inhibitor 2 ameliorated mitochondrial dysfunction and apoptosis in oleic acid-induced non-alcoholic fatty liver disease model

BCATc inhibitor 2 ameliorated mitochondrial dysfunction and apoptosis in oleic acid-induced non-alcoholic fatty liver disease model

Nonalcoholic fatty liver disease (NAFLD) is a prevalent hepatic disease in the world. Disorders of branched chain amino acid (BCAA) metabolism is involved in various diseases. In this study, we aim to explore the role of BCAA metabolism in the development of NAFLD and the protective effect of BCATc...

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Bibliographic Details
Main Authors: Zhuo Lu, Gui-Feng Sun, Xiao-An Pan, Xin-Hui Qu, Ping Yang, Zhi-Ping Chen, Xiao-Jian Han, Tao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
NAFLD
BCTAc inhibitor 2
mitochondrial dysfunction
apoptosis
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1025551/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1025551/full

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