Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2‐negative metastatic breast cancer

Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2‐negative metastatic breast cancer

Modern technologies enable detection and characterization of circulating tumor cells (CTC) in peripheral blood samples. Thus, CTC have attracted interest as markers for therapeutic response in breast cancer. First studies have incorporated CTC analyses to guide therapeutic interventions and stratifi...

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Bibliographic Details
Main Authors: Christin Gasch, Theresa Oldopp, Oliver Mauermann, Tobias M. Gorges, Antje Andreas, Cornelia Coith, Volkmar Müller, Tanja Fehm, Wolfgang Janni, Klaus Pantel, Sabine Riethdorf
Format: Article
Language:English
Published: Wiley 2016-10-01
Series:Molecular Oncology
Subjects:
Metastatic breast cancer
HER2
Circulating tumor cells
PIK3CA
Online Access:https://doi.org/10.1016/j.molonc.2016.07.005

Internet

https://doi.org/10.1016/j.molonc.2016.07.005

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