Inverse Regulation of Cartilage Neogenesis at Physiologically Relevant Calcium Conditions by Human Articular Chondrocytes and Mesenchymal Stromal Cells

Inverse Regulation of Cartilage Neogenesis at Physiologically Relevant Calcium Conditions by Human Articular Chondrocytes and Mesenchymal Stromal Cells

Elaborate bioreactor cultivation or expensive growth factor supplementation can enhance extracellular matrix production in engineered neocartilage to provide sufficient mechanical resistance. We here investigated whether raising extracellular calcium levels in chondrogenic cultures to physiologicall...

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Bibliographic Details
Main Authors: Tim Hammersen, Justyna Buchert, Severin Zietzschmann, Solvig Diederichs, Wiltrud Richter
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
extracellular matrix
tissue engineering
parathyroid hormone-related peptide
stem cells
chondrogenesis
Online Access:https://www.mdpi.com/2073-4409/12/12/1659

Internet

https://www.mdpi.com/2073-4409/12/12/1659

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