BAMBI regulates macrophages inducing the differentiation of Treg through the TGF-β pathway in chronic obstructive pulmonary disease

BAMBI regulates macrophages inducing the differentiation of Treg through the TGF-β pathway in chronic obstructive pulmonary disease

Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by continuous flow limitation and the immune system including macrophages and regulatory T lymphocytes (Tregs) is involved in COPD pathogenesis. In our previous study, we investigated that TGF-β/BAMBI pathway was assoc...

Full description

Bibliographic Details
Main Authors: Sheng-Wen Sun, Long Chen, Mei Zhou, Jiang-Hua Wu, Zhao-Ji Meng, Hong-Li Han, Shuai-Ying Miao, Chen-Chen Zhu, Xian-Zhi Xiong
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Respiratory Research
Subjects:
COPD
M2 macrophages
Regulatory T lymphocytes
TGF-β/Smad signalling pathway
BAMBI
Online Access:http://link.springer.com/article/10.1186/s12931-019-0988-z

Internet

http://link.springer.com/article/10.1186/s12931-019-0988-z

Similar Items