Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise

Urocortin3 (UCN3) regulates metabolic functions and is involved in cellular stress response. Although UCN3 is expressed in human adipose tissue, the association of UCN3 with obesity and diabetes remains unclear. This study investigated the effects of Type 2 diabetes (T2D) and increased body weight o...

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Bibliographic Details
Main Authors: Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Maha Hammad, Sriraman Devarajan, Jehad Abubaker, Fahd Al-Mulla, Jaakko Tuomilehto, Ali Tiss
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00762/full