Evaluation of a high-throughput peptide reactivity format assay for assessment of the skin sensitization potential of chemicals

The direct peptide reactivity assay (DPRA) is a validated method for in vitro assessment of the skin sensitization potential of chemicals. In the present work, we describe a peptide reactivity assay using 96-well plate format and systematically identified the optimal assay conditions for accurate an...

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Bibliographic Details
Main Authors: Chin Lin eWong, Ai Leen eLam, Maree Therese Smith, Sussan eGhassabian
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00053/full