Integrative Analysis of DNA Methylation and Gene Expression Identify a Three-Gene Signature for Predicting Prognosis in Lower-Grade Gliomas

Background/Aims: In the current study, we performed an integrated analysis of genome-wide methylation and gene expression data to find novel prognostic genes for lower-grade gliomas (LGGs). Methods: First, TCGA methylation data were used to identify prognostic genes associated with promoter methylat...

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Bibliographic Details
Main Authors: Wen-Jing Zeng, Yong-Long Yang, Zheng-Zheng Liu, Zhi-Peng Wen, Yan-Hong Chen, Xiao-Lei Hu, Quan Cheng, Jian Xiao, Jie Zhao, Xiao-Ping Chen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:https://www.karger.com/Article/FullText/489954