Human cytomegalovirus infection triggers a paracrine senescence loop in renal epithelial cells

Human cytomegalovirus infection triggers a paracrine senescence loop in renal epithelial cells

Abstract Human cytomegalovirus (HCMV) is an opportunistic pathogen causing severe diseases in immunosuppressed individuals. To replicate its double-stranded DNA genome, HCMV induces profound changes in cellular homeostasis that may resemble senescence. However, it remains to be determined whether HC...

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Bibliographic Details
Main Authors: Stefano Raviola, Gloria Griffante, Andrea Iannucci, Shikha Chandel, Irene Lo Cigno, Davide Lacarbonara, Valeria Caneparo, Selina Pasquero, Francesco Favero, Davide Corà, Elena Trisolini, Renzo Boldorini, Vincenzo Cantaluppi, Santo Landolfo, Marisa Gariglio, Marco De Andrea
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05957-5

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https://doi.org/10.1038/s42003-024-05957-5

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