Understanding the role of the CB1 toggle switch in interaction networks using molecular dynamics simulation

Abstract The cannabinoid receptor 1 (CB1) is a class A G-protein coupled receptor (GPCR) that can exert various effects on the human body through the endocannabinoid system. Understanding CB1 activation has many benefits for the medical use of cannabinoids. A previous study reported that CB1 has two...

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Bibliographic Details
Main Authors: Sangho Ji, Wonjin Yang, Wookyung Yu
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01767-5