Optimization of episomal reprogramming for generation of human induced pluripotent stem cells from fibroblasts

Optimization of episomal reprogramming for generation of human induced pluripotent stem cells from fibroblasts

Generation of induced pluripotent stem cells (iPSCs) by defined factors (OCT4, SOX2, C-MYC, and KLF4) from various human primary cells has been reported. Human fibroblasts have been widely used as a cellular source in reprogramming studies over recent decades. The original method of iPSC generation...

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Bibliographic Details
Main Authors: Jin Seok Bang, Na Young Choi, Minseong Lee, Kisung Ko, Hye Jeong Lee, Yo Seph Park, Dahee Jeong, Hyung-Min Chung, Kinarm Ko
Format: Article
Language:English
Published: Taylor & Francis Group 2018-03-01
Series:Animal Cells and Systems
Subjects:
Episomal vector
reprogramming
iPSC generation
integration-free
Online Access:http://dx.doi.org/10.1080/19768354.2018.1451367

Internet

http://dx.doi.org/10.1080/19768354.2018.1451367

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