Mitochondria-penetrating peptides conjugated to desferrioxamine as chelators for mitochondrial labile iron.

Mitochondria-penetrating peptides conjugated to desferrioxamine as chelators for mitochondrial labile iron.

Desferrioxamine (DFO) is a bacterial siderophore with a high affinity for iron, but low cell penetration. As part of our ongoing project focused on DFO-conjugates, we synthesized, purified, characterized and studied new mtDFOs (DFO conjugated to the Mitochondria Penetrating Peptides TAT49-57, 1A, SS...

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Bibliographic Details
Main Authors: Roxana Y P Alta, Hector A Vitorino, Dibakar Goswami, Cleber W Liria, Simon P Wisnovsky, Shana O Kelley, M Terêsa Machini, Breno P Espósito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171729&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171729&type=printable

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