Chemical modification by peroxynitrite enhances TLR4 activation of the grass pollen allergen Phl p 5

Chemical modification by peroxynitrite enhances TLR4 activation of the grass pollen allergen Phl p 5

The chemical modification of aeroallergens by reactive oxygen and nitrogen species (ROS/RNS) may contribute to the growing prevalence of respiratory allergies in industrialized countries. Post-translational modifications can alter the immunological properties of proteins, but the underlying mechanis...

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Bibliographic Details
Main Authors: Kathrin Reinmuth-Selzle, Iris Bellinghausen, Anna Lena Leifke, Anna T. Backes, Nadine Bothen, Kira Ziegler, Michael G. Weller, Joachim Saloga, Detlef Schuppan, Kurt Lucas, Ulrich Pöschl, Janine Fröhlich-Nowoisky
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Allergy
Subjects:
allergy
Bet v 1
Phl p 5
nitration
dimers
oligomers
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2023.1066392/full

Internet

https://www.frontiersin.org/articles/10.3389/falgy.2023.1066392/full

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