Polarity signaling balances epithelial contractility and mechanical resistance

Polarity signaling balances epithelial contractility and mechanical resistance

Abstract Epithelia maintain a functional barrier during tissue turnover while facing varying mechanical stress. This maintenance requires both dynamic cell rearrangements driven by actomyosin-linked intercellular adherens junctions and ability to adapt to and resist extrinsic mechanical forces enabl...

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Bibliographic Details
Main Authors: Matthias Rübsam, Robin Püllen, Frederik Tellkamp, Alessandra Bianco, Marc Peskoller, Wilhelm Bloch, Kathleen J. Green, Rudolf Merkel, Bernd Hoffmann, Sara A. Wickström, Carien M. Niessen
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33485-5

Internet

https://doi.org/10.1038/s41598-023-33485-5

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