Glycolysis Dependency as a Hallmark of <i>SF3B1</i>-Mutated Cells

Glycolysis Dependency as a Hallmark of <i>SF3B1</i>-Mutated Cells

<i>SF3B1</i> mutations are recurrent in cancer and result in aberrant splicing of a previously defined set of genes. Here, we investigated the fate of aberrant transcripts induced by mutant SF3B1 and the related functional consequences. We first demonstrate that mutant SF3B1 does not alt...

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Bibliographic Details
Main Authors: Raquel Vivet-Noguer, Malcy Tarin, Christine Canbezdi, Stephane Dayot, Lisseth Silva, Alexandre Houy, Sylvain Martineau, Virginie Mieulet, Géraldine Gentric, Damarys Loew, Bérangère Lombard, Fariba Nemati, Sophie Richon, Lea Guyonnet, Vincent Servois, Stephan Vagner, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
glycolysis
metabolism
SF3B1
splicing
uveal melanoma
Online Access:https://www.mdpi.com/2072-6694/14/9/2113

Internet

https://www.mdpi.com/2072-6694/14/9/2113

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