Magnetically Assisted Immobilization-Free Detection of microRNAs Based on the Signal Amplification of Duplex-Specific Nuclease

Magnetically Assisted Immobilization-Free Detection of microRNAs Based on the Signal Amplification of Duplex-Specific Nuclease

The double specific nuclease (DSN)-based methods for microRNAs (miRNAs) detection usually require the immobilization of DNA probes on a solid surface. However, such strategies have the drawbacks of low hybridization and cleavage efficiency caused by steric hindrance effect and high salt concentratio...

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Bibliographic Details
Main Authors: Gang Liu, Ming La, Jiwei Wang, Jiawen Liu, Yongjun Han, Lin Liu
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biosensors
Subjects:
microRNAs
double specific nuclease
magnetic bead
immobilization-free
homogeneous analysis
Online Access:https://www.mdpi.com/2079-6374/13/7/699

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https://www.mdpi.com/2079-6374/13/7/699

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