Progression of Mitral Regurgitation in Rheumatic Valve Disease: Role of Left Atrial Remodeling

IntroductionMitral regurgitation (MR) is the most common valve abnormality in rheumatic heart disease (RHD) often associated with stenosis. Although the mechanism by which MR develops in RHD is primary, longstanding volume overload with left atrial (LA) remodeling may trigger the development of seco...

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Main Authors: Nayana F. A. Gomes, Vicente Rezende Silva, Robert A. Levine, William A. M. Esteves, Marildes Luiza de Castro, Livia S. A. Passos, Jacob P. Dal-Bianco, Alexandre Negrão Pantaleão, Jose Luiz Padilha da Silva, Timothy C. Tan, Walderez O. Dutra, Elena Aikawa, Judy Hung, Maria Carmo P. Nunes
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.862382/full