Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis

Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis

Lipid metabolism is profoundly dysregulated in amyotrophic lateral sclerosis (ALS), yet the lipid composition of the white matter, where the myelinated axons of motor neurons are located, remains uncharacterised. We aimed to comprehensively characterise how myelin is altered in ALS by assessing its...

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Bibliographic Details
Main Authors: Gemma L. Sadler, Katherine N. Lewis, Vinod K. Narayana, David P. De Souza, Joel Mason, Catriona McLean, David G. Gonsalvez, Bradley J. Turner, Samantha K. Barton
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Metabolites
Subjects:
ALS
myelin
lipid metabolism
Online Access:https://www.mdpi.com/2218-1989/12/6/554

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https://www.mdpi.com/2218-1989/12/6/554

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