Impact of vaccination on hospitalization and mortality from COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience

Impact of vaccination on hospitalization and mortality from COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience

BackgroundIndividuals with primary and secondary immunodeficiency (PID/SID) were shown to be at risk of poor outcomes during the early stages of the SARS-CoV-2 pandemic. SARS-CoV-2 vaccines demonstrate reduced immunogenicity in these patients.ObjectivesTo understand whether the risk of severe COVID-...

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Bibliographic Details
Main Authors: Adrian M. Shields, Susan Tadros, Adam Al-Hakim, Jeremy M. Nell, Me Me Nay Lin, Michele Chan, Sarah Goddard, John Dempster, Magdalena Dziadzio, Smita Y. Patel, Shuayb Elkalifa, Aarnoud Huissoon, Christopher J. A. Duncan, Archana Herwadkar, Sujoy Khan, Claire Bethune, Suzanne Elcombe, James Thaventhiran, Paul Klenerman, David M. Lowe, Sinisa Savic, Siobhan O. Burns, Alex G. Richter
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
COVID-19
CVID
inborn errors of immunity
primary immunodeficiency
secondary immunodeficiency
vaccination
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.984376/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.984376/full

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