Butyrate suppresses abnormal proliferation in colonic epithelial cells under diabetic state by targeting HMGB1

Butyrate is widely accepted as a proliferation inhibitor in colon cancer but less thoroughly characterized in the colonic epithelium of objects with type 2 diabetes mellitus. The present study investigated the regulatory effect of butyrate on proliferation, the related molecule high-mobility group b...

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Bibliographic Details
Main Authors: Si-Yi Wang, Jie-Yao Li, Ji-Hao Xu, Zhong-Sheng Xia, Di Cheng, Wa Zhong, Yu Lai, Tao Yu, Qi-Kui Chen
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861318301634