Role of stearoyl CoA desaturase 1 in resistance of colon cancer cells to 5-fluorouracil

Objective To construct a 5-fluorouracil (5-FU)-resistant colon cancer cell line, and to investigate the role of stearoyl CoA desaturase 1 (SCD1) in the resistance of colon cancer cells to 5-FU. Methods Drug resistance to 5-FU was induced in colon cancer cell line HCT116 by increasing the concentrati...

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Détails bibliographiques
Auteurs principaux: ZHOU Hongxu, DONG Yan, LI Jianjun
Format: Article
Langue:zho
Publié: Editorial Office of Journal of Third Military Medical University 2021-03-01
Collection:Di-san junyi daxue xuebao
Sujets:
Accès en ligne:https://aammt.tmmu.edu.cn/Upload/rhtml/202009227.htm