New insight into antiphospholipid syndrome: antibodies to β2glycoprotein I-domain 5 fail to induce thrombi in rats

Clinical studies have reported different diagnostic/predictive values of antibodies to domain 1 or 4/5 of β2glycoproteinI in terms of risk of thrombosis and pregnancy complications in patients with antiphospholipid syndrome. To obtain direct evidence for the pathogenic role of anti-domain 1 or anti-...

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Bibliographic Details
Main Authors: Paolo Durigutto, Claudia Grossi, Maria Orietta Borghi, Paolo Macor, Francesca Pregnolato, Elena Raschi, Michael P. Myers, Philip G. de Groot, Pier Luigi Meroni, Francesco Tedesco
Format: Article
Language:English
Published: Ferrata Storti Foundation 2019-04-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/8856