Cellular and Molecular Biological Alterations after Photon, Proton, and Carbon Ions Irradiation in Human Chondrosarcoma Cells Linked with High-Quality Physics Data

Cellular and Molecular Biological Alterations after Photon, Proton, and Carbon Ions Irradiation in Human Chondrosarcoma Cells Linked with High-Quality Physics Data

Chondrosarcomas are particularly difficult to treat due to their resistance to chemotherapy and radiotherapy. However, particle therapy can enhance local control and patient survival rates. To improve our understanding of the basic cellular radiation response, as a function of dose and linear energy...

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Bibliographic Details
Main Authors: Birgit Lohberger, Sandra Barna, Dietmar Glänzer, Nicole Eck, Sylvia Kerschbaum-Gruber, Katharina Stasny, Andreas Leithner, Dietmar Georg
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
chondrosarcoma
proton irradiation
carbon ions
DNA repair
cell cycle
particle therapy
Online Access:https://www.mdpi.com/1422-0067/23/19/11464

Internet

https://www.mdpi.com/1422-0067/23/19/11464

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