Co-inhibition of TIGIT and PD-1/PD-L1 in Cancer Immunotherapy: Mechanisms and Clinical Trials

Abstract Over the past decade, immune checkpoint inhibitors (ICIs) have emerged as a revolutionary cancer treatment modality, offering long-lasting responses and survival benefits for a substantial number of cancer patients. However, the response rates to ICIs vary significantly among individuals an...

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Bibliographic Details
Main Authors: Xianjing Chu, Wentao Tian, Ziqi Wang, Jing Zhang, Rongrong Zhou
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-023-01800-3