Platelet derived exosomes disrupt endothelial cell monolayer integrity and enhance vascular inflammation in dengue patients

Platelet derived exosomes disrupt endothelial cell monolayer integrity and enhance vascular inflammation in dengue patients

BackgroundThrombocytopenia is the most notable phenomenon in dengue. Activation status of platelets and interaction of platelets with endothelium contribute towards dengue disease pathogenesis. Platelets are the major cell types known to release extracellular vesicles, especially exosomes in circula...

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Bibliographic Details
Main Authors: Sayali Vedpathak, Archana Sharma, Sonali Palkar, Varsha R. Bhatt, Vishwanath Chandrashekhar Patil, Arjun L. Kakrani, AkhileshChandra Mishra, Deepak Bhosle, Vidya A. Arankalle, Shubham Shrivastava
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
dengue virus
platelets
exosomes
platelet-derived exosomes
vascular inflammation
sVCAM-1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285162/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285162/full

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