MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation

MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation

The molecules and mechanisms pertinent to the low immunogenicity of undifferentiated embryonic stem cells (ESCs) remain poorly understood. Here, we provide evidence that milk fat globule epidermal growth factor 8 (MFG-E8) is a vital mediator in this phenomenon and directly suppresses T cell immune r...

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Bibliographic Details
Main Authors: Yuan Tan, Bodour AlKhamees, Deyong Jia, Li Li, Jean-François Couture, Daniel Figeys, Masahisa Jinushi, Lisheng Wang
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115002672

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http://www.sciencedirect.com/science/article/pii/S2213671115002672

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