The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33

The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33

IL-33 is a new member of the IL-1 family cytokines, which is expressed by different types of immune cells and non-immune cells. IL-33 is constitutively expressed in the nucleus, where it can act as a transcriptional regulator. So far, no direct target for nuclear IL-33 has been identified, and the r...

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Bibliographic Details
Main Authors: Yingmeng Ni, Lianqin Tao, Chen Chen, Huihui Song, Zhiyuan Li, Yayi Gao, Jia Nie, Miranda Piccioni, Guochao Shi, Bin Li
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:International Journal of Molecular Sciences
Subjects:
IL-33
ubiquitin-specific protease 17 (USP17)
IL-13
DNA binding
deubiquitinase
Online Access:http://www.mdpi.com/1422-0067/16/11/26063

Internet

http://www.mdpi.com/1422-0067/16/11/26063

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