Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation: A novel approach to atherosclerosis therapy

Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation: A novel approach to atherosclerosis therapy

Toll-like receptor 3 (TLR3), as an important pattern recognition receptor (PRR), dominates the innate and adaptive immunity regulating many acute and chronic inflammatory diseases. Atherosclerosis is proved as an inflammatory disease, and inflammatory events involved in the entire process of initiat...

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Bibliographic Details
Main Authors: Xiaohong Cen, Baoqu Wang, Yuqing Liang, Yanlin Chen, Yu Xiao, Shaohua Du, Kutty Selva Nandakumar, Hang Yin, Shuwen Liu, Kui Cheng
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Toll-like receptor 3
Atherosclerosis
Small molecule
Inflammation
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522002672

Internet

http://www.sciencedirect.com/science/article/pii/S2211383522002672

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