Dysregulation of Ceramide Metabolism Is Linked to Iron Deposition and Activation of Related Pathways in the Aorta of Atherosclerotic Miniature Pigs

Dysregulation of Ceramide Metabolism Is Linked to Iron Deposition and Activation of Related Pathways in the Aorta of Atherosclerotic Miniature Pigs

The miniature pig is a suitable animal model for investigating human cardiovascular diseases. Nevertheless, the alterations in lipid metabolism within atherosclerotic plaques of miniature pigs, along with the underlying mechanisms, remain to be comprehensively elucidated. In this study, we aim to ex...

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Bibliographic Details
Main Authors: Zhaowei Cai, Liqun Deng, Yingying Fan, Yujie Ren, Yun Ling, Jue Tu, Yueqin Cai, Xiaoping Xu, Minli Chen
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Antioxidants
Subjects:
atherosclerosis
lipidomics
ceramide
iron
oxidative stress
miniature pigs
Online Access:https://www.mdpi.com/2076-3921/13/1/4

Internet

https://www.mdpi.com/2076-3921/13/1/4

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