An Emerging Role of TIM3 Expression on T Cells in Chronic Kidney Inflammation

T cell immunoglobulin domain and mucin domain 3 (TIM3) was initially identified as an inhibitory molecule on IFNγ-producing T cells. Further research discovered the broad expression of TIM3 on different immune cells binding to multiple ligands. Apart from its suppressive effects on the Th1 cells, re...

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Bibliographic Details
Main Authors: Can Lu, Huihui Chen, Chang Wang, Fei Yang, Jun Li, Hong Liu, Guochun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.798683/full