DARPP-32 is a robust integrator of dopamine and glutamate signals.

Integration of neurotransmitter and neuromodulator signals in the striatum plays a central role in the functions and dysfunctions of the basal ganglia. DARPP-32 is a key actor of this integration in the GABAergic medium-size spiny neurons, in particular in response to dopamine and glutamate. When ph...

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Bibliographic Details
Main Authors: Eric Fernandez, Renaud Schiappa, Jean-Antoine Girault, Nicolas Le Novère
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1761654?pdf=render