Tenofovir Hot-Melt Granulation using Gelucire<sup>®</sup> to Develop Sustained-Release Vaginal Systems for Weekly Protection against Sexual Transmission of HIV
Hot-melt granulation is a technique used to obtain granules by dispersing a drug in polymers at a high temperature. Tenofovir, an antiretroviral drug with proven activity as a vaginal microbicide, was dispersed in melted Gelucire<sup>®</sup> (or a mixture of different Gelucire&l...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-03-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/11/3/137 |