Cell Cycle Stage and DNA Repair Pathway Influence CRISPR/Cas9 Gene Editing Efficiency in Porcine Embryos

Cell Cycle Stage and DNA Repair Pathway Influence CRISPR/Cas9 Gene Editing Efficiency in Porcine Embryos

CRISPR/Cas9 technology is a powerful tool used for genome manipulation in different cell types and species. However, as with all new technologies, it still requires improvements. Different factors can affect CRISPR/Cas efficiency in zygotes, which influence the total cost and complexity for creating...

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Bibliographic Details
Main Authors: Karina Gutierrez, Werner G. Glanzner, Mariana P. de Macedo, Vitor B. Rissi, Naomi Dicks, Rodrigo C. Bohrer, Hernan Baldassarre, Luis B. Agellon, Vilceu Bordignon
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Life
Subjects:
cell cycle
DNA repair
gene editing
pigs
zygotes
Online Access:https://www.mdpi.com/2075-1729/12/2/171

Internet

https://www.mdpi.com/2075-1729/12/2/171

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