Identification of COVID-19-Associated DNA Methylation Variations by Integrating Methylation Array and scRNA-Seq Data at Cell-Type Resolution

Identification of COVID-19-Associated DNA Methylation Variations by Integrating Methylation Array and scRNA-Seq Data at Cell-Type Resolution

Single-cell transcriptome studies have revealed immune dysfunction in COVID-19 patients, including lymphopenia, T cell exhaustion, and increased levels of pro-inflammatory cytokines, while DNA methylation plays an important role in the regulation of immune response and inflammatory response. The spe...

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Bibliographic Details
Main Authors: Guoliang Wang, Zhuang Xiong, Fei Yang, Xinchang Zheng, Wenting Zong, Rujiao Li, Yiming Bao
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Genes
Subjects:
COVID-19
DNA methylation
methylation array
scRNA-seq
DNAm variation gene
Online Access:https://www.mdpi.com/2073-4425/13/7/1109

Internet

https://www.mdpi.com/2073-4425/13/7/1109

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